Process of and product from treating marrow.



UNITED STATES PATENT OFFICE.

EMANUEL KLEIN, OF NEW YORK, N. Y.

PROCESS OF, AND PRODUCT FROM TREATING MARROW.

Specification of Letters Patent.

Patented Aug. 6, 1907.

Application filed November 9,1906. Serial No. 286,493.

To all whom it may concern:

Be it known that I, EMANUEL Knsnn a citizen of the United States, and a resident of theborough of Manhattan, city, county, and State of New York, have invented certain new and usefullmprovements in Processes of and Productsfrom Treating Marrow, of which the following is a specification. 4 I

This .invention' relates to a new manufacture from the fatty matter of marrow. v

It is known that marrow contains about 95 per cent. of fat, which when analyzed, is shown to contain a mixture of palrnitic and stearic acid, both acids occurring as glycerids. From this fatty matter of marrow I produce a new product which is the purifiedsubstance separated from the marrow, from all parts of the animal organism which may be employed for medical, pharmaceutical, chemical andindustrial uses.

In the manufacture of the substance I proceed as follows: First, the fresh raw marrow is disintegrated aiter which the 'mass is thoroughly kneaded and'washed in cold water so as to remove the coagulated blood, dirt i and other impurities. Following this preliminary cleansing operation, after the water has been removed, the mass is subjected to heat at a temperature of not over 150 degrees centigrade, which effects a separation of the-fatty substances fromthe cellular tissue,- lyinphatics, graves and the like, which at this stage in the process either precipitates or rises above the mass and which is then removable, after which the product allowed to cool when it will thicken, -This product is then stirred and subjected to heat by the use of superheated steam, preferably directly introduced into the mass, or heated by other means, while being stirred,

- until a temperature of about 250 degrees centigrade is' purifies the glycerid and drives out acroliuwhich.

obtained for a time not exceeding two hours which forms as such during the decomposition created'by the heating process. At the same time this process isbeing carried out, some well'known means'is employed for cooling the mass to prevent its 'too rapid heating thereby preventing burning or scorchingwhich, if

permitted, .would result inthediscoloration and by this mode the massisenabled to be subjected to the heating process for a much longer time without the liability of' burning it. When 'the mass ,has been heated at a temperatureof250 degrees'centigrade for two hours, and the steam as well as the cooling application is shut off, while in said heated condition it is further purified by treatment with some suitable menstruum such as alcohol, etc., and the is stirred until all of it has been thoroughly subjected tothe influence of said menstruum. This treatment will eliminate the objectionable color or odor of-the product by dissolving or oxidizing the matter to which the color or odor is due and rising on top of the mass may be removed leaving the underlying product colorless and odorless, 'After this treatmentiwith a liquid menstruum has taken place the stirring is discontinued and as-the mass cools, it separates into two layers, the

upper being the menstruum which may then be with-v drawn. The mass is again heated to 250 degrees centigrade after which it is filtered through some organic or inorganic filtering material, such as marble-dust, burned deers bones etc, used in connection with asbestos filtering. v The menstruum may, if stable, be purified for utilization again.- 1f alcohol is employed the quantity found to be practicable is 2 parts of alco- .liol to 1 part of marrow. The resultant is an odorless substance consisting of a mixture of fatty acids and higher alcohols of thefatty series. Thisis of a butter like consistency, light yellow in coloni'isinsoluble in water or alcohol, will not become rancid and may be utilized for medical, pharmaceutical, chemical or industrial purposes.

jectlng murrow to disintegration, washing the same,-heatlng' tlie same at about 150 degrees centigrade, filtering the resulting product, subjecting ltto the action ota menstruum and-removing the menstruum from the-product.

2. The process of treating marrow whlch consistsln subjecting crude marrow to disintegration, washing the saute, heating the'sarne to about 15.0 degrees cutlgrslde, removing the cellular substances, heating it to about 250 degrees centlgrnde, subjecting-it tothe action of a men-- struum and removing the menstruum fromthe product. t

' 3. The process of m nufacture from the tatty'matter'et "marrow, which consist in subjecting titer-aw marrow toy heat atone temperature to free it fromcellulnr'tlss'ue and the like, then cooling \he product, and then hosting the some at a higher temperature and stirring the samewhlle' being heated to remove acrolein, then stopplngthe heating operation and purifying the product while still hot with a.

menstruum, stirring the product, then heating and than removing the menstruum from the product then fllterl'ng the remainder.

' 4. A product from treating marrow, constltutlnga ho mogeneous, odorless, non-ranclflable mass of light-yellow colonbeing lrrmllrlllnln water or alcohol, having a specific gravity at 15 'degrees centlgrade of 0.931 to 9.938, a melt ing'polut of 37 to 45 degrees nu l a solidifying point of 29 0.931 M20938, a limiting point of 37 to 45 degrees and a 10 a lo 31 degrees.

solidifying point of 29 to 31 degrees. V in testimony whereof Lhave signed this specification in 5. A product from treating mm-rowyconstltutlng a hothe presence f two subfi'crmng witnesses mogeneous odorless, nonq-anclfialile mass of butter-like consistency and light yellow color, comprising substan- I tinlly a mixkure of iatty acids and higher alcohols o! the Witnesses: fatty set-lea, the product being insoluble in waterpr alcp- Own A. FOSTER, ml nnvlnga specific gravityvat 15 degrees centigrade of A. L. OBnmu.

EMANUEL KLEIN. 

